By Hugo Kubinyi, Gerd Folkers, Yvonne C. Martin
Volumes 2 and three of the 3D QSAR in Drug layout sequence objective to check the development being made in CoMFA and different 3D QSAR techniques because the e-book of the hugely winning first quantity approximately 4 years in the past. quantity 2 (Ligand-Protein Interactions and Molecular Similarity) divides into 3 sections facing Ligand-Protein Interactions, Quantum Chemical versions and Molecular Dynamics Simulations, and Pharmacophore Modelling and Molecular Similarity, respectively. quantity three (Recent Advances) is additionally divided into 3 sections, particularly 3D QSAR technique: CoMFA and comparable methods, Receptor versions and different 3D QSAR methods, and 3D QSAR functions. greater than seventy uncommon scientists have contributed approximately 40 studies in their paintings and similar study to those volumes that are of remarkable caliber and timeliness. those works current an up to date insurance of the most recent advancements in all fields of 3D QSAR.
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Extra resources for 3D QSAR in Drug Design: Volume 3: Recent Advances (Three-Dimensional Quantitative Structure Activity Relationships, Volume 3)
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B. , 3D-QSAR of angiotensin-converting enzyme and lliermolysin inhibitors: A comparison of CoMFA models based on deduced and experimentally determined active site geometries, J. Am. Chem. , 115(1993) 5372–5384. , Merz, A. , CoMFA: Scope and limitations, In Kubinyi, H. ) 3D QSAR in d r u g d e s i g n : Theory, methods and applications, ESCOM, Leiden, The N e t h e r l a n d s , 1993, pp. 583–618. , Giolitti, A. , Three-dimensional QSAR of human immunodeficiency virus (I) protease inhibitors: 1 .
3D QSAR in Drug Design: Volume 3: Recent Advances (Three-Dimensional Quantitative Structure Activity Relationships, Volume 3) by Hugo Kubinyi, Gerd Folkers, Yvonne C. Martin